Thisassaykitisusedtoevaluatethecellsenescenceinvitro.Itisforresearchuseonly.Notforuseinanimals,humans,ordiagnosticprocedures
Normalmammaliancellsdivideforalimitednumberofpopulationdoublingsandeventuallyenteranarrestedstateinwhichthecellsremainalive,butdonotproliferateinresponsetomitogens,andassumeacharacteristicenlarged,flattenedmorphology.Thisprocess,termedsenescence,isthoughttobeatumorsuppressivemechanismandunderlyingcauseofaging.Senescence-associatedβ-galactosidase(SA-β-gal)isawidelyusedbiochemicalmakerforassessingsenescenceinculturedcells.The
SciencellCellSenescenceAssayprovideaneasy-to-usemethodtodetectSA-β-galbystainingcellswith5-bromo-4-chloro-3-indolyl-β-D-galactopyranoside(X-gal)atpH6.0,apHconditionthatsuppresslysosomalβ-galactosidaseactivitysufficientlytoensurethatnonsenescentcellsremainunstained.
Specifications:
CatalogNo. | 8058 |
CountryofManufacture | UnitedStates |
ProductCode | CSA |
Size/Quantity | 50tests/35mmplate |
ProductUse | Thisassaykitisusedtoevaluatethecellsenescenceinvitro.Itisforresearchuseonly.Notforuseinanimals,humans,ordiagnosticprocedures |
Storage | -20°C |
ShippingInfo | Dryice. |
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