Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
AcidicFibroblastGrowthFactor(aFGF)isamemberoftheFGFfamilyofmitogenicpeptideswhichiscomprisedofatleast23proteinsshowing35-55%aminoacidsequenceconservation.UnlikeotherFGFfamilymembers,aFGFandbasicFGF(bFGF)lacksignalpeptidesandaresecretedviaadifferentmechanismotherthantheclassicalproteinsecretionpathway.aFGFhasbeendetectedinlargeamountsinthebrain.OthercellsknowntoexpressaFGFincludehepatocytes,vascularsmoothmusclecells,CNSneurons,skeletalmusclecells,fibroblasts,keratinocytes,endothelialcells,intestinalcolumnarepitheliumcells,pituitarybasophilsandacidophils.AswithotherFGF’s,aFGFexhibitsconsiderablespeciescrossreactivity.aFGFandbFGFstimulatetheproliferationofallcellsofmesodermalorigin,andmanycellsofneuroectodermal,ectodermalandendodermalorigin.

Specifications:

CatalogNo.	104-01
CountryofManufacture	UnitedStates
ProductCode	rhaFGF
Size/Quantity	10μg
ProductUse	Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
Storage	Storeat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.FormaximalstABIlity,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfo	Dryice
Synonyms	FGF-1,HBGF-1,ECGF-beta(endothelialcellgrowthfactorbeta),FibroblastGrowthFactor-acidic
AASequence	MFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
Source	Escherichiacoli
MolecularWeight	Approximately15.8kDa,asinglenon-glycosylatedpolypeptidechaincontaining140aminoacids.
Purity	>95%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivity	Fullybiologicallyactive.TheED50is
PhysicalAppearance	Whitelyophilizedpowder.
Formulation	Lyophilizedfroma0.2μmfilteredconcentrated(1mg/ml)solutioninPBS,pH7.4.
Endotoxin
Reconstitution	Reconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.

美国Sciencell 研究实验室（ScienCell）是一家生物技术公司，其宗旨是研究和细胞和细胞发育相关的实验和治疗的产品。该ScienCell技术提供了高质量的正常人体和动物的各种细胞，细胞培养基和试剂，中补充，细胞源性核糖核酸，基因和蛋白质的研究团体。在ScienCell科学家还在研究和开发细胞治疗策略，将大大改善通过实现细胞的能力，打击贩运退行性疾病的生活质量。我们的总部设在加利福尼亚州圣迭戈，并于1999年设立。