Sciencell™BovinePlasmaVitronectinispurifiedfrombovineplasmabyaffinitychromatography.ItissuppliedasasterilesolutioninDulbecco"sPhosphate-BufferedSaline(DPBS).
Caution:Ifhandledimproperly,somecomponentsofthisproductmaypresentahealthhazard.Takeappropriateprecautionswhenhandlingthisproduct,includingthewearingofprotectiveclothingandeyewear.Disposeofproperly.
Vitronectinisaglycoproteinfoundinplasmaandextracellularmatrix(ECM).Itisasoluble,disulfide-linkeddimer,composedofa75kDaanda65kDapeptidechain.Inplasma,vitronectinispredominantlyfoundasasinglechainmonomer[1].TheN-terminalofvitronectincontainsmultiplebindingsitesforavarietyofstructures.VitronectinisinvolvedinanumberofBIOLOGicalfunctionsincludingcelladhesion,spreADIng,migration,proliferation,extracellularanchoring,fibrinolysis,hemostasis,andcomplementimmunedefense[2,3,4].Vitronectincanbeusedforcoatingtissueculturesurfacestopromotecelladhesion,proliferation,anddifferentiation.
ScienCell™BovinePlasmaVitronectinispurifiedfrombovineplasmabyaffinitychromatography[5].ItissuppliedasasterilesolutioninDulbecco"sPhosphate-BufferedSaline(DPBS).Optimalconditionsforcellattachmentmustbedeterminedforeachcelllineandapplication.
ProductSpecification
Quantity: 100µg
Concentration: 0.4mg/ml
Storagebuffer: DPBS,pH7.4
CatalogNo. | 8538 |
CountryofManufacture | UnitedStates |
ProductCode | BPV |
Size/Quantity | 100μg |
ProductUse | THESEPRODUCTSAREFORRESEARCHUSEONLY.Notapprovedforhumanorveterinaryuse,forapplicationtohumansoranimals,orforuseinclinicalorinvitroprocedures. |
Storage | Itisrecommendedthattheproductbealiquotedandstoredat-80°C.Vitronectinshouldbethawedslowlyat2-8°Cwithnoagitation.Anyprecipitatethatispresentcanberemovedbycentrifugation.Avoidrepeatedfreeze/thawcycles. |
ShippingInfo | Dryice. |
References | 1.VuentoM,KorkolainenM,KuuselaP,HolttaE.(1985)"Isolationofanovelcell-attachmentandspreading-promotingproteinfromhumanserum."BiochemJ.227:421-7.2.HaymanEG,PierschbacherMD,SuzukiS,RuoslahtiE.(1985)"Vitronectin--amajorcellattachmentpromotingproteininfetalbovineserum."ExpCellRes.160:245-58.3.AkiyamaKS.(1999)"PurificationofVitronectin."CurrentProtocolsinCellBiology.10.6.1-10.6.5 |
美国Sciencell 研究实验室(ScienCell)是一家生物技术公司,其宗旨是研究和细胞和细胞发育相关的实验和治疗的产品。该ScienCell技术提供了高质量的正常人体和动物的各种细胞,细胞培养基和试剂,中补充,细胞源性核糖核酸,基因和蛋白质的研究团体。在ScienCell科学家还在研究和开发细胞治疗策略,将大大改善通过实现细胞的能力,打击贩运退行性疾病的生活质量。我们的总部设在加利福尼亚州圣迭戈,并于1999年设立。