Mesenchymalstemcells(MSC)areawell-characterizedpopulationofadultstemcells.MSChavethepotentialtodevelopintomaturecellsthatproducefat,cartilage,bone,tendons,andmuscle.Theseproperties,incombinationwiththeirdevelopmentalplasticity,havegeneratedtremendousinterestbecauseofthepotentialuseofMSCinregenerativemedicine.FetallunghasbeenidentifiedasarichsourceofMSCandstudieshaveshownthatMSCcandifferentiateintoneuralcells,inadditiontotheirmesenchymaldifferentiationpotential[1].MSChavealsobeenshowntoenhancetheengraftmentofhumanumbilicalcordblood-derivedCD34hematopoieticcellsinimmunodeficientmice[2].FlowcytometricanalysisshowedthatfetallungMSCexpressCD13,CD29,CD44,CD90,CD105,CD166,andHLA-ABC.
HPMSCfromSciencellResearchLaboratoriesareisolatedfromhumanlungtissue.HPMSCarecryopreservedatpassageoneanddeliveredfrozen.Eachvialcontains>5x10^5cellsin1mlvolume.HPMSCarecharacterizedbyimmunofluorescencewithantibodiesspecifictoCD73,CD90andCD105.HPMSCarenegativeforHIV-1,HBV,HCV,mycoplasma,bacteria,yeastandfungi.HPMSCareguaranteedtofurtherexpandfor15populationdoublingsundertheconditionsprovidedbyScienCellResearchLaboratories.
RecommendedMedium
ItisrecommendedtouseMesenchymalStemCellMedium(MSCM,Cat.#7501)forculturingHPMSCinvitro.
CatalogNo. | 7540 |
CountryofManufacture | UnitedStates |
ProductCode | HPMSC |
Size/Quantity | 5x10^5cells/vial |
ProductUse | HPMSCareforresearchuseonly.Itisnotapprovedforhumanoranimaluse,orforapplicationininvitrodiagnosticprocedures. |
Storage | Directlyandimmediatelytransfercellsfromdryicetoliquidnitrogenuponreceivingandkeepthecellsinliquidnitrogenuntilcellcultureisneededforexperiments. |
ShippingInfo | Dryice. |
References | [1].FanCG,TangFW,ZhangQJ,LuSH,LiuHY,ZhaoZM,LiuB,HanZB,HanZC(2005)Characterizationandneuraldifferentiationoffetallungmesenchymalstemcells.CellTransplant.14:311-321.[2].NoortWA,KruisselbrinkAB,in"tAnkerPS,etal.(2002)Mesenchymalstemcellspromoteengraftmentofhumanumbilicalcordblood-derivedCD34(+)cellsinNOD/SCIDmice.Exp.Hematol.30:870-878. |
美国Sciencell 研究实验室(ScienCell)是一家生物技术公司,其宗旨是研究和细胞和细胞发育相关的实验和治疗的产品。该ScienCell技术提供了高质量的正常人体和动物的各种细胞,细胞培养基和试剂,中补充,细胞源性核糖核酸,基因和蛋白质的研究团体。在ScienCell科学家还在研究和开发细胞治疗策略,将大大改善通过实现细胞的能力,打击贩运退行性疾病的生活质量。我们的总部设在加利福尼亚州圣迭戈,并于1999年设立。