Thisassaykitisusedtoevaluatetubeformationinvitro.Itisforresearchuseonly.Notforuseinanimals,humans,ordiagnosticprocedures.
Angiogenesis,ortheformationofnewbloodvessels,playsanimportantroleinmanyphysiological(e.g.woundhealing)andpathological(e.g.tumorgrowthandinflammationdisease)processes.Asacomplexmulti-stepprocess,angiogenesisinvolvesdegradationofbasementmembrane,proliferationandmigrationofendothelialcellsintoextracellularmatrix(ECM),followedbyalignmentandreorganizationofendothelialcellsintothree-dimensionaltubularstructureandformationofnewbasementmembrane.Specifically,thecriticalstepoftheformationofthree-dimensionaltubularstructurebyendothelialcellsistheobjectiveofmanyinvivoandinvitroangiogenesisassaystoscreenefficacyofbothpro-andantiangiogenicagents.TheSciencellInVitroTubeFormationAssayprovidesaconvenientsystemtomeasuretheformationofthree-dimensionaltubularstructurebyenodothelialcellswhenculturedonanECMgelofbasementmembraneextract.TheECMgel,whichispreparedfromEngelbrethHolm-Swarm(EHS)sarcomaproducedinmice,consistsoflaminin,collagenIV,heparansulfateproteoglycan,entactinandotherminorcomponentsoptimizedfortubeformation.Withthissystem,tubeformationcanbeachievedwithin6-18hours,withtheearliestsignsoftubularstructureshownupafter3-4hours.TheAssayalsoprovidesacolorimetriccellstainingreagentforbetterexamination.

Specifications:

CatalogNo.	8158
CountryofManufacture	UnitedStates
ProductCode	IVTFA
Size/Quantity	50tests
ProductUse	Thisassaykitisusedtoevaluatetubeformationinvitro.Itisforresearchuseonly.Notforuseinanimals,humans,ordiagnosticprocedures.
Storage	-20°C
ShippingInfo	Dryice.

美国Sciencell 研究实验室（ScienCell）是一家生物技术公司，其宗旨是研究和细胞和细胞发育相关的实验和治疗的产品。该ScienCell技术提供了高质量的正常人体和动物的各种细胞，细胞培养基和试剂，中补充，细胞源性核糖核酸，基因和蛋白质的研究团体。在ScienCell科学家还在研究和开发细胞治疗策略，将大大改善通过实现细胞的能力，打击贩运退行性疾病的生活质量。我们的总部设在加利福尼亚州圣迭戈，并于1999年设立。