HexokinaseAssaykitcouldmeasureHKactivityofsamplesfromcellsandtissue.Thisproductisforresearchpurposesonlyandnotforuseinanimals,humans,ordiagnosticprocedures.
Hexokinase(HK),whichphosphorylatesglucoseandgeneratesglucose-6-phosphateforglycolysis,playsanimportantroleinglucosemetabolism.HKdeficiencyleadstoseverehumandiseasessuchasX-linkedmusculardystrophyandarareautosomalrecessivehemolyticanemia.Ontheotherhand,increasedHKactivityisdetectedinvarioushumantumorsandisassociatedwithmetastasis.In
SciencellHexokinaseAssaykit,glucoseisconvertedtoglucose-6-phosphatebyHK,theglucose-6-phosphateisoxidizedbyglucose-6-phosphatedehydrogenasetoformNADPH,whichcanconvertanearlycolorlessprobetoanintenselycoloredproduct,whichexhibitsmaximumabsorbanceat490nm,isproportionaltotheactivityofHKinthesample.
Specifications:
| CatalogNo. | 8408 |
| CountryofManufacture | UnitedStates |
| ProductCode | HK |
| Size/Quantity | 100tests |
| ProductUse | HexokinaeAssaykitcouldmeasureHKactivityofsamplesfromcellsandtissue.Thisproductisforresearchpurposesonlyandnotforuseinanimals,humans,ordiagnosticprocedures. |
| Storage | Storein-20°C |
| ShippingInfo | Thekitwouldbeshippedondryice. |
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