ThePDHAssaykitmeasuresthePDHactivityofdifferenttypesofsamples,suchastissuesandcelllysate.Thisproductisforresearchpurposesonlyandnotforuseinanimals,humans,ordiagnosticprocedures.
Pyruvatedehydrogenase(PDH)isthefirstcomponentenzymeofthepyruvatedehydrogenasecomplex(PDC).Asakeyregulatoroftricarboxylicacid(TCA)cycleflux,thePDCcatalyzestheconversionofpyruvateintoacetyl-CoAandregulatestheentryofglucose-carbonsintotheTCAcycle.PDCdeficiencyisoneofthemostcommonneurodegenerativedisordersassociatedwithabnormalmitochondrialmetabolism.Thiscolorimetricassayisbasedonpyruvatedehydrogenase-catalyzedoxidationofpyruvate,wheretheresultingNADHcanthenconvertanearlycolorlessprobetoacoloredproduct.TheintensityofthecoloredproductisproportionaltotheamountofPDHinthesample,exhibitingmaximumabsorbanceat440nm.
Specifications:
CatalogNo. | 8658 |
CountryofManufacture | UnitedStates |
ProductCode | PDH |
Size/Quantity | 100Tests |
ProductUse | ThePDHAssaykitmeasuresthePDHactivityofdifferenttypesofsamples,suchastissuesandcelllysate.Thisproductisforresearchpurposesonlyandnotforuseinanimals,humans,ordiagnosticprocedures. |
Storage | Storein-20°C |
ShippingInfo | Shippedondryice. |
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